This profile identifies the additional constraints, extensions, and value sets that build on and extend [Substance](http://hl7.org/fhir/R4/substance.html) that are supported. 

A [Substance](http://hl7.org/fhir/R4/substance.html) resource is used within the context of a referencing resource: [Medication](http://hl7.org/fhir/R4/medication.html) or [Substance](http://hl7.org/fhir/R4/substance.html) resource. 

This profile is designed to set a core Substance standard in the context of:
* Querying substances referenced in Medication resources
* Recording or updating a substance referenced by a Medication resource


#### Profile specific guidance
None.
